US Series-A VCs investing in SaaS

Today, we selected 20 active US Series-A VCs from our database, investing in SaaS startups.  

Our team reviewed, checked, and enriched the list with the necessary data.

(The first 10 are free for all subscribers, the last 10 are open to our premium subscribers.)

Here goes:

• Allrise Capital — Irvine-based Allrise Capital is a multi-strategy investment firm deploying capital across venture, real estate, and special situations in the U.S. and select emerging markets. The firm emphasizes SaaS, real estate, and frontier growth opportunities, using deep fundamental research to identify asymmetric risk/reward investments.

• AltaIR Capital — San Francisco-based AltaIR Capital invests globally in early and growth-stage startups, primarily in the U.S., Israel, and Europe. Its focus spans SaaS, fintech, insurtech, AI, and digital health. The firm backs ambitious founders building disruptive technologies that shape the future of work and life.

• B37 Ventures — Based in Silicon Valley, B37 Ventures invests in Series A–C tech startups with a SaaS emphasis. The firm creates synergies between global corporations and startups, driving both innovation and scale. Its platform enables entrepreneurs and enterprises to collaborate and unlock shareholder value.

• Byers Capital — San Francisco-based Byers Capital invests in Series A and B technology and biotech ventures. The firm backs innovative entrepreneurs in SaaS and life sciences who are building transformative solutions with strong growth potential.

• Collective Capital Ventures — Auburn-based Collective Capital Ventures operates a self-directed venture model that enables investors to access diversified portfolios of 30+ high-growth startups. With a focus on AI, ML, and SaaS, the firm democratizes access to institutional-quality venture opportunities.

• Fathom Capital — San Francisco-based Fathom Capital is an early-stage VC focused on enterprise software and IT infrastructure. The firm invests in SaaS startups solving mission-critical problems for global businesses, backing teams with the potential to build category-leading companies.

• Fellows Fund — Sunnyvale-based Fellows Fund connects AI pioneers with next-generation innovators. The firm invests in SaaS and AI/ML startups applying advanced research to broad, real-world challenges. Its model emphasizes mentorship and collaboration with leading AI inventors.

• FINTOP Capital — Nashville-based FINTOP Capital invests in B2B SaaS companies within fintech. With a hands-on approach and deep sector expertise, the firm partners with founders building scalable financial technology platforms for enterprises and institutions.

• Flexcap — New York-based Flexcap backs early-stage enterprise SaaS and marketplace startups. The firm looks for category-defining businesses at the Series A stage and provides strategic support to help them scale into market leaders.

• Fortius Ventures — San Francisco-based Fortius Ventures invests in Series A and B SaaS companies. With a selective approach, Fortius prioritizes quality over volume, partnering only in top-tier deals where it has unique insights and conviction.

That’s all for today. Have a great day!

Tzakhi

Founder of InvestorsLists.VC and Meet.Capital 

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