US seed VCs investing in healthcare

Today, we selected 20 active US seed VCs from our database, investing in healthcare startups.  

Our team reviewed, checked, and enriched the list with the necessary data.

(The first 10 are free for all subscribers, the last 10 are open to our premium subscribers.)

Here goes:

• Epsilon Health Investors — Based in Washington, D.C., Epsilon Health Investors is a venture capital firm focused on digital healthcare and SaaS. Founded by industry leaders Steven and Gregory Epstein, the firm manages capital for health systems and executives, leveraging deep sector experience to back early-stage healthcare innovators.

• Excelerate Health Ventures — Located in Durham, North Carolina, Excelerate Health Ventures is a seed-stage VC firm investing in healthcare software and tech-enabled services. The firm partners with early healthcare innovators, supporting their mission to improve patient care and digital health outcomes.

• F-Prime Capital — Based in Cambridge, Massachusetts, F-Prime Capital is a venture capital firm investing in seed-stage healthcare and technology companies. The firm seeks to back transformative innovations that advance global health, life sciences, and digital healthcare ecosystems.

• Fitt Capital — Headquartered in Pittsburgh, Pennsylvania, Fitt Capital is a seed-stage venture capital firm investing in healthcare, mental health, sports, and wellness startups. The firm partners with mission-driven founders redefining well-being through innovation, technology, and purpose-driven products.

• Forward Ventures — Located in San Diego, California, Forward Ventures is a life-science-focused VC firm managing over $500 million in capital. It invests in biotechnology, healthcare, and SaaS companies across stages, emphasizing transformative health innovations and partnerships with leading researchers.

• Frist Cressey Ventures — Based in Nashville, Tennessee, Frist Cressey Ventures is a healthcare-focused venture capital firm investing in seed-stage SaaS and digital health companies. The firm combines capital with strategic support to drive systemic change and improve healthcare outcomes nationwide.

• Grand Ventures — Headquartered in Grand Rapids, Michigan, Grand Ventures is an early-stage VC fund investing in B2B SaaS companies in fintech, healthcare, and manufacturing. The firm partners with exceptional entrepreneurs across North America, providing seed capital and long-term guidance through early growth.

• Gratitude Railroad — Based in Park City, Utah, Gratitude Railroad is an impact-focused venture capital firm investing in healthcare, wellness, and SaaS companies. The firm supports purpose-driven founders building businesses that deliver both strong financial returns and lasting social impact.

• Grounded Capital — Operating from San Francisco, California, Grounded Capital is a venture firm investing in energy, healthcare, and SaaS. With over $2 billion under management, the firm applies a holistic, systems-based approach to align financial success with environmental and social well-being.

• Hatteras Venture Partners — Located in Durham, North Carolina, Hatteras Venture Partners is a healthcare VC firm investing in biopharma, medical devices, and healthcare IT. The firm supports science-driven startups from leading research institutions, nurturing breakthrough innovations in human medicine.

That’s all for today. Have a great day!

Tzakhi

Founder of InvestorsLists.VC and Meet.Capital 

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