US seed accelerators

A curated list of active US seed accelerators investing in startups.

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Our team reviewed, checked, and enriched the list with the necessary data.

Here goes:

HudsonAlpha AgTech — Madison-based accelerator investing at the seed stage across agriculture, agtech, and SaaS. Powered by gener8tor, HudsonAlpha AgTech invests up to $100K in high-growth startups annually, combining common equity and optional convertible note investments to support companies operating at the forefront of agricultural innovation.

Hula — Burlington-based accelerator investing at the seed stage across biotechnology and climate. Hula operates as a technology coworking campus, business accelerator, and venture capital fund, supporting Vermont-based startups with early-stage funding, mentorship, and connectivity to help scale innovative and disruptive technologies.

L.A. Libations — El Segundo-based accelerator and incubator investing at the seed stage across consumer products, services, fintech, healthcare, mental health, and wellness. L.A. Libations focuses on next-generation beverage brands, supporting founders building innovative, health-driven products through hands-on incubation, acceleration, and entrepreneurial support.

MassChallenge — Boston-based accelerator investing at the seed stage across fintech and impact. MassChallenge is a global nonprofit startup accelerator and competition, focused on supporting high-impact, early-stage entrepreneurs by providing programs, exposure, and resources designed to help founders build scalable and meaningful companies.

SSC Venture Partners — Boston-based venture capital firm and accelerator investing at the seed stage in education-focused startups. SSC Venture Partners supports Boston College alumni and students through seed funding, a twelve-week summer accelerator, mentorship, and educational programming to help founders successfully launch early-stage companies.

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The House Fund — Berkeley-based accelerator and venture capital fund investing at the seed and A-round stages across AI, ML, and SaaS. The House Fund focuses on Berkeley-founded startups, supporting alumni, faculty, and students through its AI Accelerator, early capital, and deep access to technical mentors and partners.

UpTech Accelerator — Covington-based accelerator investing at the seed stage across education, fintech, and transportation. UpTech supports data-driven startups through a six-month accelerator program that combines intensive entrepreneurship education, one-on-one mentoring, and community engagement to prepare companies for equity funding.

XRC Ventures — New York-based accelerator investing at the seed stage across consumer products, services, fintech, hardware, healthcare, and transportation. XRC Ventures operates as a venture capital firm and accelerator, supporting founders building the next generation of retail technology, consumer healthtech, and consumer goods companies.

Xontogeny — Boston-based accelerator investing at the seed and A-round stages across biotechnology, hardware, and SaaS. Xontogeny collaborates with scientific founders and first-time CEOs, providing seed capital, industry expertise, and operational support to advance life sciences technologies toward clinical proof-of-concept.

Upekkha AI SaaS Accelerator — San Francisco-based accelerator investing at the seed and A-round stages across AI, ML, SaaS, consumer products, and services. Upekkha is an AI SaaS Accelerator fund helping Indian founders build global software brands, leveraging more than 15 years of experience and networks built with over 3,000 founders to support globally scalable companies.

Have a great day!

Tzakhi

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