US SaaS VCs

Today, we selected 20 active US VCs from our database, investing in SaaS startups.  

Our team reviewed, checked, and enriched the list with the necessary data.

(The first 10 are free for all subscribers, the last 10 are open to our premium subscribers.)

Here goes:

• Biospring Partners — New York-based Biospring Partners is a growth equity firm investing in life sciences technology. With expertise across biotech, SaaS, and enterprise software, the firm supports B2B services and tools driving industry innovation. Biospring leverages deep experience in both science and technology to help scale companies transforming the life sciences ecosystem.

• BioStar Capital — Petoskey-based BioStar Capital is a venture partnership specializing in healthcare and SaaS. It focuses on medical device technologies, particularly in cardiovascular and orthopedic medicine. The firm partners with entrepreneurs advancing breakthrough medical innovations that improve patient outcomes.

• Blackstone Tactical Opportunities — New York-based Blackstone Tactical Opportunities is an opportunistic investing platform within Blackstone. With a flexible mandate, the firm seeks SaaS and technology-driven opportunities globally, targeting high-potential companies across industries. Its strategy adapts to shifting markets while maintaining disciplined growth investing.

• Blackwing — San Diego-based Blackwing is a venture capital firm investing in early-stage companies across the U.S. and Europe. With a focus on SaaS and technology-driven businesses, the firm supports founders at critical inflection points. Blackwing helps startups accelerate growth and scale internationally.

• Blossom Street Ventures — Dallas-based Blossom Street Ventures invests in SaaS companies generating $3M–$30M in ARR. The firm backs pragmatic and resourceful founders through growth rounds and special situations such as extensions and cap table cleanups. Typical checks range from $1M to $4M, with commitments made within weeks.

• Blue Delta Capital Partners — McLean-based Blue Delta Capital Partners is a growth-stage venture firm focused on U.S. government services. Concentrating on SaaS and technology-enabled sectors, the firm provides equity and strategic input in non-controlling positions. Since inception, it has invested in 24 companies with multiple exits and dividends.

• Blueprint Equity — La Jolla-based Blueprint Equity is a growth equity firm investing in market-leading enterprise businesses. With a focus on SaaS and technology-enabled companies, the firm partners with founders to accelerate scaling. Its approach combines capital with operational expertise to build sustainable growth.

• Blueprint For The Culture — New York-based Blueprint For The Culture backs Black founders, Black-led ventures, and entrepreneurs of color. Focused on SaaS and consumer sectors, it combines capital with cultural influence. The firm helps build iconic brands that create paradigm shifts and lasting social impact.

• Boathouse Capital — Wayne-based Boathouse Capital is a Philadelphia-area private equity firm managing $650M. It invests up to $100M in SaaS, healthcare IT, and tech-enabled services. With a flexible approach, Boathouse provides equity or debt on both control and non-control bases, supporting accelerated middle-market growth.

• Boot64 Ventures — Metairie-based Boot64 Ventures funds Louisiana entrepreneurs in need of startup capital. By targeting SaaS and early-stage small businesses, the firm aims to drive job creation and strengthen the state’s economy. Boot64 supports founders ready to scale impactful ventures.

That’s all for today. Have a great day!

Tzakhi

Founder of InvestorsLists.VC and Meet.Capital 

PS: Want more? Save 25% on our yearly plan + full investor database. Get it now→

Special offers and discounts from recommended partners:

1. The investor message templates that helped raise millions by Meet.Capital →

2. The best equity crowdfunding platform: ​Wefunder​ (save up to $10,000 on platform fees with this link)

3. The best design services for your pitch deck: ​DesignForDecks​ (use promo code CHOSEN15 to save 15%)

4. Learn to unlock capital from family offices with ​The Glassbox​ (Save 10% with promo code Meetcapital2025)