San Francisco Series-A VCs

A curated list of active San Francisco Series-A VCs investing in startups.

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Today, we selected 10 active San Francisco Series-A VCs from our database, investing in startups.  

Our team reviewed, checked, and enriched the list with the necessary data.

Here goes:

• Climactic VC — Based in San Francisco, Climactic VC invests at the A-round stage in visionary founders tackling climate change and sustainability. The firm supports companies developing transformative technologies to address the planet’s most urgent environmental challenges.

• Climate Tech Circle — San Francisco’s Climate Tech Circle is a venture capital firm focused on early-stage climate technology. Through its Circle Fund, it enables climate investors to participate in scalable, impactful innovation combating global environmental issues.

• Common Sense Growth — Headquartered in San Francisco, Common Sense Growth invests at the A-round stage in media and entertainment ventures. As a subsidiary of Common Sense Media, it backs products and services that empower kids and families to thrive in the digital era.

• Counterpart Ventures — San Francisco–based Counterpart Ventures is a life cycle VC fund investing at the A-round stage. It focuses on building authentic, trust-based relationships with founders to support durable, long-term company growth.

• DCVC Bio — Operating from San Francisco, DCVC Bio invests at the A-round stage in life science ventures powered by deep tech. The firm backs startups leveraging advanced technologies to accelerate innovation across healthcare and biotechnology.

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• Define Ventures — San Francisco’s Define Ventures is an early-stage VC firm focused on digital health. Investing at the A-round stage, it supports healthcare entrepreneurs who are transforming patient experiences and improving health outcomes through technology.

• Derive Ventures — Based in San Francisco, Derive Ventures invests at the A-round stage in hospitality, travel, and leisure startups. The firm targets innovative business concepts reshaping core travel sectors and helps founders navigate this complex global industry.

• Dolby Family Ventures — San Francisco–based Dolby Family Ventures is an early-stage VC firm dedicated to building great technology companies. It invests at the A-round stage, continuing the Dolby family’s legacy of supporting innovation and creativity in tech.

• Draft Ventures — Based in San Francisco, Draft Ventures is a collaborative online fund investing at the A-round stage in fintech and climate. It finances, advises, and accelerates early-stage companies working toward scalable, sustainable innovation.

• Ecosystem Integrity Fund — San Francisco’s Ecosystem Integrity Fund is a venture capital firm investing at the A-round stage in renewable energy and green chemistry. It targets sectors driving ecological sustainability and the transition to a low-carbon economy.

We have also put together a list of 200 impact and climate investors.

Our premium subscribers can access the list with all of the necessary data, including:

Name, website, HQ location, LinkedIn company page, description/thesis, preferred stages, preferred domains, and contact email.

To view the full premium list, upgrade now at a no-brainer price:

That’s all for today. Have a great day!

Tzakhi

Founder of InvestorsLists.VC and Meet.Capital 

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