San Francisco seed VCs investing in AI/ML

Today, we selected 10 active San Francisco seed VCs from our database, investing in AI/ML startups.  

Our team reviewed, checked, and enriched the list with the necessary data.

Here goes:

• AllMobile Fund — San Francisco–based AllMobile Fund is a seed-stage VC investing in disruptive mobile startups. Focused on AI and ML, the firm builds a synergistic global ecosystem of mobile innovators, providing both capital and value-added operational support to accelerate time-to-market while maintaining lean startup principles.

• Ashbury Ventures — Operating from San Francisco, Ashbury Ventures is the investment arm of Ashbury Legal. As a seed-stage VC, it focuses on AI, ML, blockchain, and cryptocurrency ventures, leveraging deep legal and regulatory expertise in crypto markets to back forward-looking founders.

• Bain Capital Ventures — San Francisco’s Bain Capital Ventures (BCV) invests from seed to growth stages across B2B software, fintech, and SaaS. Managing over $10 billion, BCV partners with visionary founders building transformative companies that redefine industries and global commerce.

• Benchmark — Based in San Francisco and Woodside, Benchmark is a seed-stage venture capital firm backing entrepreneurs at the earliest stages. It focuses on AI, consumer services, enterprise software, and marketplaces, helping founders turn startups into category-defining global companies.

• Capital 49 — San Francisco–based Capital 49 is a seed-stage VC created by Airwallex founders. The firm invests in early, high-growth companies within the Airwallex ecosystem, targeting AI, fintech, SaaS, and consumer tech ventures that leverage financial infrastructure innovation.

• E1 Ventures — Headquartered in San Francisco, E1 Ventures is a data-driven VC firm applying AI and data science to early-stage investing. Using its proprietary E/Quant platform, the firm identifies prime deep tech, SaaS, and ML opportunities through advanced predictive and semantic analysis.

• L2 Iterative Venture — Based in San Francisco, L2 Iterative Venture backs blockchain pioneers building the next digital era. Focused on seed-stage investments in AI, Web3, and SaaS, the firm supports founders driving societal transformation through convergent technologies.

• Lattice Fund — San Francisco’s Lattice Fund is an early-stage VC focused on crypto and Web3. Investing in AI and blockchain-enabled startups, it helps founders build sustainable open-source ecosystems through community-driven growth and long-term partnerships.

• Long Term Impact — Operating from San Francisco, Long Term Impact invests in healthcare and longevity technologies. As a seed-stage VC, it backs therapeutics and platforms targeting aging reversal and enhanced human health, aiming to extend healthy lifespans beyond 120 years.

• Long Venture Partners — San Francisco–based Long Venture Partners invests in early-stage tech companies across China and the U.S. Focused on AI, fintech, and consumer internet sectors, it combines global vision with local market insight to empower ambitious founders.

We have also put together a list of 100 San Francisco VCs A round.

Our premium subscribers can access the list with all of the necessary data, including:

Name, website, HQ location, LinkedIn company page, description/thesis, preferred stages, preferred domains, and contact email.

That’s all for today. Have a great day!

Tzakhi

Founder of InvestorsLists.VC and Meet.Capital 

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