Boston seed VCs

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Our team reviewed, checked, and enriched the list with the necessary data.

Here goes:

• Fine Structure Venture — Boston-based A-round venture capital firm focused on early-stage investments in disruptive scientific and technological innovation. Fine Structure Ventures is affiliated with FMR LLC, the parent company of Fidelity Investments, and supports companies developing breakthrough technologies with the potential to reshape industries through rigorous research and long-term innovation.

• GPVC — Boston-based A-round venture capital firm investing in artificial intelligence, machine learning, and cybersecurity. GPVC backs companies developing leading technologies across data-driven and frontier sectors, focusing on teams building scalable, defensible products that address complex technical challenges and unlock new capabilities in AI, security, and adjacent fields.

• HighSage Ventures — Boston-based A-round venture capital firm investing in defense and security. HighSage Ventures is funded by permanent capital and invests across public and private companies, supporting businesses with the goal of long-term value creation that ultimately enables philanthropic initiatives across a range of mission-driven efforts.

• HLM Venture Partners — Boston-based A-round venture capital firm focused on healthcare. HLM Venture Partners invests in healthcare technology companies, supporting teams developing innovative solutions that improve care delivery, clinical outcomes, and operational efficiency across the healthcare ecosystem through technology-enabled business models.

• Iaso Ventures — Boston-based A-round venture capital firm investing in healthcare. Iaso Ventures focuses on early-stage companies in the brain health sector, leveraging an investor-operator team and strategic partner network to help founders scale impactful solutions that advance neurological health and improve patient outcomes.

• IGNIA — Boston-based A-round venture capital firm focused on early-stage technology companies. IGNIA invests in global entrepreneurs developing tech solutions that address fundamental pain points in Latin America, supporting founders building scalable businesses that target large, underserved markets through practical and impactful innovation.

• J2 Ventures — Boston-based A-round venture capital firm investing in defense and security. J2 Ventures supports entrepreneurs tackling the world’s hardest national security challenges, providing capital and expertise to help private companies navigate the public sector while building mission-critical technologies.

• Longwood Fund — Boston-based A-round venture capital firm focused on healthcare. Longwood Fund finances science-based companies developing novel medical solutions, backing teams translating breakthrough research into products that address unmet clinical needs and advance patient care.

• LRVHealth — Boston-based A-round venture capital firm investing in healthcare. LRVHealth operates an “Inside Healthcare” platform, drawing on deep experience from investors, operators, and advisors to support companies improving healthcare delivery, efficiency, and outcomes from within the system.

• Material Impact — Boston-based A-round venture capital firm focused on deep tech. Material Impact builds companies powered by material science, championing bold ideas that leverage advanced materials and engineering to create transformative technologies with real-world industrial and societal impact.

Have a great day!

Tzakhi

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